Edvotek - Sickle Cell Gene Detection (Dna-Based) Classroom Educational Kit 8 gels, 45 minutes Time Range, Refrigerated - Fisher Scientific - S94670

This item may require 7-10 Business Days to process and prepare for shipping.

Product Information: EDUCATIONAL KIT, SICKLE CELL GENE DETECTION

• To investigate the restriction enzyme that discriminates between hba (normal) and hbs (disease) genes and perform a simulated test on a patient
• Genetically inherited diseases in humans can be caused by a single nucleotide mutation resulting in a change
• Such a substitution can affect the structure and function of a critical protein, rendering it partially or completely nonfunctional
• A classic example is hemoglobin in sickle cell anemia
• Agarose gel-based experiment designed for DNA staining and visualization with InstaStain methylene blue
• Demonstrates the use of a restriction enzyme that discriminates between the normal and sickle cell hemoglobin genes
• This experiment does not contain human DNA
• Requires electrophoresis apparatus, power supply, automatic micropipet and tips, balance, microwave or hot plate, visualization system
• Includes: Instructions, Ready-to-load Quickstrip DNA samples, Ultraspec agarose powder, practice gel loading solution, electrophoresis buffer, Instastain blue and Flashblue